ETHZ - ETH Zurich - Institute of Process Engineering

Organisation description

General description:

ETH Zurich has been a science and technology university with an outstanding research record
(including 21 Nobel laureates connected to it) since 1855. ETH Zurich is the study, research
and work place of 18,000 people from 80 nations (25% of which are women). About 350
professors in 15 departments teach to about 13,000 students (3,000 of which are Ph.D. students).

Expertise

The project partner ETHZ involves two research groups of the ETHZ (ETHZa, ETHZb).
The Separation Processes Laboratory (ETHZa) has expertise in: - purification of biopharmaceuticals by preparative chromatography; - production of micro-particles of organic species by crystallization and precipitation; - CO₂ capture and storage.
Bioprocess laboratory (ETHZb):

- enzyme and fermentation processes integrated with product removal, such as SMB
- synthetic biology
- parallelization and miniaturization of bioprocess development

Facilities

ATR-FTIR; Raman; FBRM (2); PVM; XRPD; DSC; Sympatec Elos; Coulter
Counter; magnetic suspension balances (2); Akta-SMB unit; Akta purifier; HPLC; GC (2);
Ion Chromatograph; SFC; diverse set-ups for crystallization and precipitation; polarimeters
(2).
We would need additionally for the project: one HPLC unit w/ autosampler; and one
set-up for crystallization w/ thermostat.

Laboratories equipped for microbiological, biochemical/enzyme-technological, molecular
biological procedures, high-.throughput screening (96-well plate format - centrifuges,
pipetting stations, 96-well sprectro- and fluorimeter), process development: Triplequat MS,
(c)HPLC, fermentation, downstream processing, sequencing, HTP-fluorescence analysis
Newly required for the project: HTP-polarimeter

Key personnel involved in INTENANT

Prof. Dr. Marco Mazzotti (ETHZa) is head of the Separation Processes Laboratory and is
main representative of ETHZ with INTENANT. He has published about 150 peer-reviewed
articles, has graduated 17 Ph.D. students and is currently advising 12; Dr. Thes Bäbler
is post-doc research associate; Lorenzo Codan and Christian Langel are Ph.D. students.

Prof. Sven Panke (ETHZb) is head of the Bioprocess Laboratory at ETH Zurich that currently
in-cludes 11 PhD students and 6 post doctoral researchers

Other European projects the organisation has been involved in:

DeCARBit/FP7; FP6:
Eurobiosyn (Co-ordinator, #01274), Nanomot (#029084), Synbiocomm (Co-ordinator,
#028809), Emergence (Co-ordinator, #043338)

Role in the project

WP3 (coordinator), WP4, WP6. Minor contribution: WP1, WP7, WP8.
WP5 (coordinator), participates in WPs 1, 2, and 6

Link

http://www.ipe.mavt.ethz.ch