Max Planck Institute for Dynamics of Complex Technical Systems

Introduction

From the Max Planck Institute for Dynamics of Complex Technical Systems (MPI) in Magdeburg, Germany two research groups are involved within the IntEnant-Project.

"Physical and Chemical Foundations of Process Engineering" - MPIa (Prof. Dr.-Ing. Andreas Seidel-Morgenstern)

"Process Synthesis and Process Dynamics" - MPIb (Prof. Dr.-Ing. Achim Kienle)

These two groups are well equipped for high level experimental investigations in the project. There is access to various HPLC and SMB units and batch & continuous crystallizers. Further, there is a long term experience in computer aided modeling.

The competences

MPIa
The main fields of activity are in the areas of chemical reaction engineering, preparative chromatography, technical crystallization and process modelling and simulation. Several model substances and industrial relevant compounds have been investigated in the last years.

MPIb
The research of the group focuses on computer aided modeling, analysis, synthesis and control of complex chemical processes. One main field of application are integrated chemical processes combining chemical reaction and separation processes in various ways.
Additionally, new theoretical methods for computer aided synthesis of combined reaction distillation processes are developed. These comprise shortcut methods as well as new strategies for global optimization of MINLP problems. Further, the group has strong expertise in theoretical methdos for chromatographic processes. Experimental verification is often done in close collaboration with the other research groups at the MPI.

The Goals in IntEnant

An important goal of MPI is to determine physical and chemical data and parameters that are related to the chemical engineering and bioengineering processes investigated (e.g. solid liquid phase equilibria).
Main objectives are also to develop methods, tools, and criteria for determination of optimal combinations of individual process steps (synthesis, racemization, crystallization, chromatography), and to determine optimal operating conditions for such processes. First reference solutions will be obtained from simulation studies and rigorous mathematical optimization for model compounds, for which an almost complete set of chemical and thermodynamic properties is available. Afterwards, several other industrial relevant compounds will be taken into consideration.

Selected Publications

Sundmacher, K., Kienle A., Seidel-Morgenstern A., Integrated Chemical Processes, Wiley-VCH, 2005.

Kaspereit M., Gedicke K., Zahn V., Mahoney A., Seidel-Morgenstern A., Shortcut method for evaluation and design of a hybrid process for enantioseparations, J. Chrom. A, 1092, 2005, 43 - 54

Lorenz H., Polenske D., Seidel-Morgenstern A., Application of preferential crystallization to resolve racemic compounds in a hybrid process, Chirality, 18, 2006, 828 - 840

Gangadwala, J., Kienle A., MINLP Optimization of butyl acetate synthesis, Chem. Eng. Proc., 46, 2007, 107 - 118

Gedicke, Kaspereit, Beckmann, Budde, Lorenz, Seidel-Morgenstern: Conceptual Design & Fesibility Study of Combining Continuous Chromatography and Crystallization for Stereoisomer Separations, Chem. Eng. Res. Des., 85, 2007, 928 - 936

Kaspereit, M., Seidel-Morgenstern, A., Kienle, A.: Design of simulated moving bed processes under reduced purity requirements. Journal of Chromatography A, 1162, 2-13 (2007)

Press

Press release (German)

Links

MPIa: http://www.mpi-magdeburg.mpg.de/research/groups/pcg/
seidel-morgenstern

mpi-magdeburg.mpg.de

MPIb: http://www.mpi-magdeburg.mpg.de/research/groups/pspd/
kienle

mpi-magdeburg.mpg.de